Cardiovascular Effects of 1 Year of Alagebrium and Endurance Exercise Training in Healthy Older Individuals

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منابع مشابه

Cardiovascular effects of 1 year of alagebrium and endurance exercise training in healthy older individuals.

BACKGROUND Lifelong exercise training maintains a youthful compliance of the left ventricle (LV), whereas a year of exercise training started later in life fails to reverse LV stiffening, possibly because of accumulation of irreversible advanced glycation end products. Alagebrium breaks advanced glycation end product crosslinks and improves LV stiffness in aged animals. However, it is unclear w...

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Background—Healthy but sedentary aging leads to cardiovascular stiffening, whereas life-long endurance training preserves left ventricular (LV) compliance. However, it is unknown whether exercise training started later in life can reverse the effects of sedentary behavior on the heart. Methods and Results—Twelve sedentary seniors and 12 Masters athletes were thoroughly screened for comorbiditie...

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Cardiovascular effects of 1 year of progressive and vigorous exercise training in previously sedentary individuals older than 65 years of age.

BACKGROUND Healthy but sedentary aging leads to cardiovascular stiffening, whereas life-long endurance training preserves left ventricular (LV) compliance. However, it is unknown whether exercise training started later in life can reverse the effects of sedentary behavior on the heart. METHODS AND RESULTS Twelve sedentary seniors and 12 Masters athletes were thoroughly screened for comorbidit...

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ژورنال

عنوان ژورنال: Circulation: Heart Failure

سال: 2013

ISSN: 1941-3289,1941-3297

DOI: 10.1161/circheartfailure.113.000440